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Updated: Nov 11, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

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Refractory heart failure with LBBB - Pause before CRT

Sachin Yalagudri1, Muthiah Subramanian1, Daljeet Saggu1

  • 1Asian Institute of Gastroenterology, Gachibowli, Hyderabad, India.

Indian Pacing and Electrophysiology Journal
|March 29, 2021
PubMed

In this report, we describe complete disappearance of LBBB with normalization of LV function in two patients with cardiac sarcoidosis (CS) after immunosuppressive therapy. Both of these patients were ideal Class IA candidates for CRT (Complete LBBB, QRS ≥ 150 ms, EF < 30%). If CS is identified early, immunosuppressive treatment can lead to not only improvement of left ventricular function but also disappearance of the left bundle branch block. Timely diagnosis and management of CS obviated the need of CRT in these patients. It may be reasonable to evaluate all non-ischemic cardiomyopathies for underlying reversible causes prior to CRT implantation.

Keywords:
Cardiac resynchronization therapyCardiac sarcoidosisLeft bundle branch block

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