Caputo SIR model for COVID-19 under optimized fractional order

Ali S Alshomrani1, Malik Z Ullah1, Dumitru Baleanu2,3,4

  • 1Department of Mathematics, King Abdul Aziz University, Jeddah, Saudi Arabia.

Advances in Difference Equations
|March 29, 2021
PubMed
Summary

This study adapted a Susceptible-Infectious-Recovered (SIR) model using a Caputo derivative to analyze COVID-19 data in Pakistan. The modified SIR model demonstrated a better fit to real-world epidemic data, highlighting social distancing as a key control measure.

Related Concept Videos

Parameters Affecting Nonlinear Elimination: Zero-Order Input, First-Order Absorption and Two-Compartment Model01:13

Parameters Affecting Nonlinear Elimination: Zero-Order Input, First-Order Absorption and Two-Compartment Model

Drugs administered through various routes can lead to nonlinear elimination, resulting in complex pharmacokinetic behaviors crucial to understanding efficacious drug dosing.
When a drug is administered through a constant intravenous infusion and eliminated via nonlinear pharmacokinetics, it follows zero-order input. For example, oral drugs undergo first-order absorption upon administration and are eliminated through nonlinear pharmacokinetics.
In the case of subcutaneously administered drugs,...
176
One-Compartment Open Model for Extravascular Administration: Zero-Order Absorption Model01:12

One-Compartment Open Model for Extravascular Administration: Zero-Order Absorption Model

Extravascular administration, such as oral or intramuscular routes, is a non-invasive drug delivery method, often preferred for ease and patient compliance. A key factor here is absorption, which dictates how quickly and effectively the drug enters the bloodstream from the administration site. Absorption follows either zero-order or first-order kinetics.
Zero-order absorption maintains a steady rate irrespective of the amount of drug left to be absorbed, making it a constant process. In the...
246
Bernoulli's Equation00:59

Bernoulli's Equation

In the middle of the nineteenth century, it was observed that two trains passing each other at a high relative speed get pulled towards each other. The same occurs when two cars pass each other at a high relative speed. The reason is that the fluid pressure drops in the region where the fluid speeds up. As the air between the trains or the cars increases in speed, its pressure reduces. The pressure on the outer parts of the vehicles is still the atmospheric pressure, while the resultant...
11.8K
One-Compartment Open Model for IV Bolus Administration: Estimation of Elimination Rate Constant, Half-Life and Volume of Distribution01:09

One-Compartment Open Model for IV Bolus Administration: Estimation of Elimination Rate Constant, Half-Life and Volume of Distribution

The one-compartment open model is a simplified approach used in pharmacokinetics to understand the distribution and elimination of a drug administered through an intravenous bolus. This model assumes rapid drug dispersal throughout the body and elimination using a first-order process. Key pharmacokinetic parameters, such as the elimination rate constant (k), half-life (t1/2), and the apparent volume of distribution (Vd), can be estimated from this model. The elimination rate is calculated...
620
Bernoulli's Equation: Problem Solving01:16

Bernoulli's Equation: Problem Solving

A Venturi meter is essential for measuring fluid flow rates in pipelines. It utilizes the relationship between fluid velocity and pressure described by Bernoulli's equation. When installed in a sewage system, the Venturi meter accurately determines the wastewater flow rate by measuring pressure differences.
The first step is to compute the cross-sectional areas of the pipe and the Venturi throat to analyze the pressure difference indicated by the pressure gauge. Next, the continuity equation is...
1.6K
One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance00:56

One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance

Clearance is a key pharmacokinetic parameter that quantifies the volume of body fluid from which a drug is entirely removed within a specific time frame. It is crucial in assessing how a drug is eliminated from the body and has critical clinical applications.
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...
193