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Optical Devices Constructed From Responsive Microgels for Polyphenols Detection
Jingying Wang1, Xieli Zhang2,3, Kaiyao Shi4
1Department of Laboratory, 15189 Accredited Laboratory, Jilin Province Drug Resistance Monitoring Center, China-Japan Union Hospital of Jilin University, Changchun, China.
Frontiers in Chemistry
|March 29, 2021
Summary
This study introduces a novel photonic device for detecting polyphenols, using a "block" concept with dopamine as a model. The device measures dopamine concentration by observing optical changes caused by dopamine film formation.
Area of Science:
- Food Chemistry
- Health Science
- Biosensing
Background:
- Polyphenols are antioxidants in foods and beverages, offering health benefits.
- Accurate measurement of polyphenol content is crucial in food chemistry and health science.
- Existing detection methods may lack sensitivity or specificity.
Purpose of the Study:
- To develop a novel microgel-based photonic device (etalon) for detecting polyphenols.
- To propose and validate a "block" concept for sensitive dopamine detection.
- To correlate optical signal changes with dopamine concentration.
Main Methods:
- Utilized a microgel-based photonic etalon.
- Employed tyrosinase to catalyze dopamine oxidation and form films on the etalon surface.
- Measured optical property changes in the etalon upon immersion in ZnCl2, influenced by the dopamine film's blocking effect.
Main Results:
- Successfully demonstrated dopamine detection using the "block" concept.
- Observed optical property changes directly related to dopamine film formation and thickness.
- Established a correlation between film thickness, dopamine concentration, and readout optical signals.
Conclusions:
- The developed microgel-based photonic etalon offers a promising method for polyphenol detection.
- The "block" concept provides a sensitive and quantifiable approach for detecting dopamine and potentially other polyphenols.
- This technology has implications for food analysis and health monitoring.

