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Abaloparatide Real-World Patient Experience Study.

Deborah T Gold1, Richard Weiss2, Tammy Beckett3

  • 1Departments of Psychiatry & Behavioral Sciences and Sociology Duke University Medical Center Durham NC USA.

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|March 29, 2021
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Summary
This summary is machine-generated.

Most patients with osteoporosis are satisfied with abaloparatide (ABL) injections, reporting high adherence due to ease of preparation, storage, and daily integration. Positive patient experiences and healthcare support contribute to treatment success.

Keywords:
ANABOLICSHEALTH SERVICES RESEARCHOSTEOPOROSIS

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Area of Science:

  • Bone Metabolism and Osteoporosis Research
  • Patient-Reported Outcomes in Therapeutics

Background:

  • Suboptimal adherence to osteoporosis treatments is a significant clinical challenge.
  • Patient experience with therapy is a potential factor influencing treatment adherence.

Purpose of the Study:

  • To describe the real-world patient experience with abaloparatide (ABL) injection in postmenopausal women at high risk for fracture.
  • To identify factors associated with patient satisfaction and adherence to ABL therapy.

Main Methods:

  • Multicenter, combined retrospective chart review and patient questionnaire study in the US.
  • Inclusion of 193 postmenopausal women at high risk for fracture.
  • Assessment of patient satisfaction, ease of preparation/storage, daily activity integration, and adherence.

Main Results:

  • 86% of patients were satisfied with the ABL regimen, citing ease of preparation (82%) and storage (87%).
  • 85% reported satisfaction with ABL's integration into daily activities, and 83% reported medium to high adherence.
  • Ease of preparation and fracture history were significantly associated with overall satisfaction.

Conclusions:

  • The majority of patients are satisfied with abaloparatide, finding it convenient and easy to prepare and store.
  • High self-reported adherence may be linked to positive patient experiences, including ease of use and healthcare provider support.
  • Addressing patient-reported bothersome attributes like injection discomfort and cost could further enhance treatment experience.