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Updated: Nov 11, 2025

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
Published on: October 11, 2018
Complications following REM sleep behavior disorder
Eva Schaeffer1, Daniela Berg1,2
1Department of Neurology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Abstract:
REM sleep behavior disorder (RBD) is gaining increasing attention as important prodromal marker for the development of neurodegenerative disorders such as Parkinson's Disease. However, the clinical relevance of this disorder and its association with other prodromal markers is often underestimated in clinical routine. We here report a case of severe clinical complications following extensive nocturnal movements due to RBD, aggravated by occurrence of additional prodromal non-motor symptoms. This case stresses the importance of recognizing RBD as a multisystem disease by all clinical disciplines.
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