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Catecholamine and blood pressure levels in paralysed preterm ventilated infants
A Greenough1, J Pool, H Lagercrantz
1Department of Child Health, King's College Hospital, Denmark Hill, London, U.K.
Early Human Development
|March 1, 1988
Abstract:
The effect of pancuronium administration on catecholamine levels and blood pressure was investigated. Noradrenaline levels prior to paralysis amongst infants fighting the ventilator were high, but were significantly reduced following treatment with pancuronium. There was no significant change in either blood pressure or adrenaline levels. Increasing peak inspiratory pressure (approx. 4 cmH2O) immediately prior to paralysis effectively prevented the hypoventilation previously associated with the administration of the first dose of pancuronium.