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Prevention of enteral radiocesium absorption by hexacyanoferrates(II) in piglets
P Nielsen1, R Fischer, H C Heinrich
1Institut für Physiologische Chemie, Universitätskrankenhaus Eppendorf, Hamburg, Federal Republic of Germany.
Experientia
|June 15, 1988
Abstract:
The efficacy of different hexacyanoferrates(II) in preventing the enteral absorption of 134Cs was studied in piglets. As compared to the controls, oral application of 134Cs together with KFe[Fe(CN)6], NH4Fe[Fe(CN)6], or Fe4[Fe(CN)6]3 resulted in a strong reduction of the 134 Cs-uptake by more than 97%. The decrease in enteral absorption depends on the dose of administered hexacyanoferrate(II), whereas differences between the compounds under study were small. The biological half-life of 134Cs in non-hexacyanoferrate(II) treated piglets was 21.6 +/- 3.3 days (mean +/- SD).