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Diol lipids are activators of protein kinase C
S E Severin1, E K Tovmasyan, V I Shvets
1M.V. Lomonosov Moscow Institute of Fine Chemical Technology, Academy of Sciences of the USSR.
FEBS Letters
|May 23, 1988
Abstract:
Diol lipids (dioleoyl- and dioctanoylethylene glycol) at relatively low concentrations (approximately 10 microM) were found to activate significantly protein kinase C in the presence of phosphatidylserine or phosphatidylinositol. Since diol lipids are widespread minor lipid constituents of many cells [(1974) Chem. Ind., 597-604], it has been suggested that they may be involved in the maintaining of basal protein kinase C activity in the absence of external stimuli.