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Related Concept Videos

Physiological Foundation of Stress01:24

Physiological Foundation of Stress

257
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
257
Stress Response System01:21

Stress Response System

446
The stress response system, also known as the fight-or-flight response, is the body's automatic physiological reaction to perceived threats. Hans Selye introduced the concept of General Adaptation Syndrome (GAS) to describe the predictable pattern of changes that occur in response to stress. GAS consists of three sequential stages: alarm, resistance, and exhaustion. This model helps explain how chronic stress can contribute to health problems.
Alarm stage
In the alarm stage, the body's...
446
Stress Concentrations01:13

Stress Concentrations

419
The concept of stress concentration is crucial for understanding how materials respond under bending stresses, particularly when there are irregularities or discontinuities in the material's geometry. Normally, stress in a symmetric member subjected to pure bending is assumed to be uniformly distributed across the entire cross-section. However, this assumption does not hold when there are variations in the cross-sectional geometry or the presence of notches and holes.
The stress...
419
Stress Concentrations01:24

Stress Concentrations

465
Stress concentration is when stress intensifies near discontinuities such as holes or abrupt cross-sectional changes in a structural member. This localized stress can often surpass the average stress within the member. The stress distribution in flat bars, either with a circular hole or varying widths connected by fillets, can be determined experimentally using a photoelastic method. The results are based on ratios of geometric parameters like the ratio of the hole's radius to the smaller...
465
Exercise Stress Test01:26

Exercise Stress Test

667
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
667
Applications of Stress01:04

Applications of Stress

476
Consider a structure made of a boom and a rod designed to support a load. These two components are connected by a pin and stabilized by brackets and pins. The boom and the rod are detached from their supports to assess the different stresses imposed on this structure, and a free-body diagram is drawn. Then, all the forces applied, including the load acting on the structure, are identified. The reaction forces exerted on both the boom and the rod are computed using the equilibrium equations.
The...
476

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Related Experiment Video

Updated: Nov 11, 2025

A Community-based Stress Management Program: Using Wearable Devices to Assess Whole Body Physiological Responses in Non-laboratory Settings
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Touch-Based Stressless Cortisol Sensing.

Wanxin Tang1,2, Lu Yin1, Juliane R Sempionatto1

  • 1Department of Nanoengineering, Center of Wearable Sensors, University of California San Diego, 9500 Gilman Dr., San Diego, CA, 92093, USA.

Advanced Materials (Deerfield Beach, Fla.)
|March 31, 2021
PubMed
Summary
This summary is machine-generated.

A new touch-based electrochemical sensor provides rapid, non-invasive detection of cortisol in sweat. This wearable device allows for simple, stress-free monitoring of cortisol levels, aiding in stress management.

Keywords:
circadian rhythmcortisolfinger-based sensorsmolecularly imprinted polymersrapid detection

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Endocrinology

Background:

  • Cortisol level monitoring is crucial for understanding stress responses.
  • Conventional cortisol detection methods are lab-based, slow, and invasive.
  • Existing wearable sensors face limitations in speed and assay complexity.

Purpose of the Study:

  • To develop a rapid, simple, and non-invasive electrochemical sensor for sweat cortisol detection.
  • To enable real-time, stress-free monitoring of cortisol fluctuations.
  • To create a wearable sensor for quantitative stress management.

Main Methods:

  • Fabrication of a touch-based molecularly imprinted polymer (MIP) electrochemical sensor.
  • Utilizing a polypyrrole coating with cortisol-imprinted sites for selective binding.
  • Incorporating Prussian blue redox probes for label-free amperometric detection.
  • Employing a porous hydrogel for rapid sweat collection from fingertips.

Main Results:

  • The sensor achieved sensitive and selective detection of sweat cortisol in 3.5 minutes.
  • Demonstrated accurate tracking of cortisol fluctuations during cold-pressor tests and circadian rhythms.
  • Validated against gold-standard immunoassay methods.
  • Developed a stretchable epidermal sensor for exercise-induced sweat cortisol monitoring.

Conclusions:

  • The developed MIP electrochemical sensor offers a rapid, non-invasive, and user-friendly method for sweat cortisol monitoring.
  • This technology facilitates convenient and stress-free assessment of the body's endocrine response to stress.
  • The sensor presents a promising tool for accessible, quantitative stress management and physiological monitoring.