Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Membrane Fluidity01:23

Membrane Fluidity

166.2K
Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.
166.2K
Membrane Fluidity01:26

Membrane Fluidity

13.6K
Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is...
13.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Phenotype Comparison in Polish Patient Cohorts with and Without Molecular Diagnosis of Dystonia.

Journal of clinical medicine·2026
Same author

A versatile nanobody platform for live and super-resolution imaging of synaptic vesicle dynamics and plasticity in rodent and human neurons.

Journal of nanobiotechnology·2026
Same author

No added cost: Emotion recognition in co-occurring ADHD and ASD.

The British journal of clinical psychology·2026
Same author

Effect of Reporting Mode and Clinical Experience on Radiologists' Gaze and Image Analysis Behavior at Chest Radiography.

Radiology·2026
Same author

Near-Infrared Emitting Fibers: Stable Jet Electrospinning Flat PbSe Quantum Dots into Poly(methyl methacrylate).

The journal of physical chemistry letters·2026
Same author

Comparison of face attention bias in adults with ASD, ADHD, or comorbid ADHD+ASD.

Social cognitive and affective neuroscience·2025

Related Experiment Video

Updated: Nov 10, 2025

Method to Visualize and Analyze Membrane Interacting Proteins by Transmission Electron Microscopy
10:49

Method to Visualize and Analyze Membrane Interacting Proteins by Transmission Electron Microscopy

Published on: March 5, 2017

13.6K

Selected tools to visualize membrane interactions.

Tobias Grothe1,2, Julia Nowak2, Reinhard Jahn1

  • 1Laboratory of Neurobiology, Max-Planck-Institute for Biophysical Chemistry, 37077, Göttingen, Germany.

European Biophysics Journal : EBJ
|March 31, 2021
PubMed
Summary
This summary is machine-generated.

Researchers developed advanced fluorescence tools to study membrane fusion and interactions. These methods, using liposomes, precisely measure distances and dynamics crucial for understanding protein-mediated vesicle fusion.

Keywords:
Fluorescence cross-correlation spectroscopyFluorescence lifetime analysisLiposomesMembrane fusion intermediatesSynaptic proteins

More Related Videos

Membrane-SPINE: A Biochemical Tool to Identify Protein-protein Interactions of Membrane Proteins In Vivo
10:53

Membrane-SPINE: A Biochemical Tool to Identify Protein-protein Interactions of Membrane Proteins In Vivo

Published on: November 7, 2013

13.9K
Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

2.7K

Related Experiment Videos

Last Updated: Nov 10, 2025

Method to Visualize and Analyze Membrane Interacting Proteins by Transmission Electron Microscopy
10:49

Method to Visualize and Analyze Membrane Interacting Proteins by Transmission Electron Microscopy

Published on: March 5, 2017

13.6K
Membrane-SPINE: A Biochemical Tool to Identify Protein-protein Interactions of Membrane Proteins In Vivo
10:53

Membrane-SPINE: A Biochemical Tool to Identify Protein-protein Interactions of Membrane Proteins In Vivo

Published on: November 7, 2013

13.9K
Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

2.7K

Area of Science:

  • Biophysics
  • Membrane Biology
  • Biochemistry

Background:

  • Fluorescence microscopy techniques are vital for studying membrane dynamics.
  • Liposomes serve as essential model systems for dissecting molecular interactions.
  • Understanding membrane fusion and docking is critical in cell biology.

Purpose of the Study:

  • To provide an overview of fluorescence-based methods for monitoring membrane fusion, docking, distances, and curvature.
  • To highlight the application of these methods in studying protein-mediated vesicle interactions.
  • To discuss the capabilities and limitations of developed techniques.

Main Methods:

  • Development of fluorescence-based assays for membrane dynamics.
  • Utilizing liposomes as model systems for controlled experiments.
  • Application of two-photon fluorescence cross-correlation spectroscopy and intramembrane Förster energy transfer.
  • Asymmetric labeling of membrane leaflets and calibrated transmembrane energy transfer for distance measurements below 10 nm.

Main Results:

  • Established fluorescence methods for monitoring membrane fusion, docking, distances, and curvature.
  • Demonstrated precise distance measurements between membranes using energy transfer.
  • Validated techniques using protein-mediated vesicle docking and fusion models.

Conclusions:

  • Developed and refined fluorescence tools offer powerful capabilities for membrane biophysics research.
  • These methods enable detailed investigation of molecular interactions driving membrane fusion.
  • The presented techniques are valuable for studying complex biological processes involving membrane dynamics.