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Updated: Nov 10, 2025

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice
Published on: November 2, 2019
[Lipedema : an unknown entity]
Vincienne Naef1, David Alvarez Martinez1, Begonia Cortes1
1Service de dermatologie et vénéréologie, Département de médecine, HUG, 1211 Genève 14.
Abstract:
Lipedema is an infrequently recognized disorder. It is characterized by bilateral painful enlargement of the legs due to abnormal depositions of subcutaneous fat, that can result in considerable disability. The diagnosis is established on the basis of medical history and clinical findings. Early diagnosis of this disorder is necessary to start adapted management and prevent progression and complications of the disease. Currently there is no curative treatment. The conservative treatment requires a multidimensional approach including manual lymph drainage, compression garments and management or prevention of obesity as well as other comorbidities. In some cases, surgery may be considered.
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