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Photopolymerized Porous Hydrogels.

Erwan Nicol¹

¹Institut des Molécules et Matériaux du Mans (IMMM), UMR 6283 CNRS Le Mans Université, Avenue Olivier Messiaen, 72085 Cedex 9 Le Mans, France.

Biomacromolecules

|April 1, 2021

Summary

This review explores photopolymerized hydrogels, focusing on controlling porosity for biomedical uses. Understanding porosity is key for tissue engineering and drug delivery applications.

Area of Science:

Biomaterials Science
Polymer Chemistry
Biomedical Engineering

Background:

Hydrogels are water-swollen polymer networks with tissue-mimicking properties, making them valuable for biomedical applications.
Controlling hydrogel porosity is critical as it dictates transport properties and cellular interactions.
Photopolymerization is a versatile technique for synthesizing hydrogels.

Purpose of the Study:

To provide an overview of photopolymerized hydrogels with a focus on porosity generation and characterization.
To review materials and methods used in creating porous photopolymerized hydrogels.
To highlight applications of these hydrogels in controlled release and tissue engineering.

Main Methods:

Review of literature on photopolymerized hydrogels.

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Presentation of polymers and photoinitiating systems for hydrogel synthesis.

Explanation of porosity generation techniques within photopolymerized hydrogels.

Overview of porosity characterization methods.

Main Results:

Photopolymerization offers powerful and versatile routes for hydrogel synthesis.
Various methods exist for generating and characterizing porosity in these hydrogels.
The generated porosity significantly impacts transport and cellular behavior.

Conclusions:

Photopolymerized hydrogels with controlled porosity are promising for biomedical applications.
Further research into porosity control enhances their utility in drug delivery and tissue engineering.
This review consolidates knowledge on synthesizing and characterizing porous hydrogels.