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Updated: Nov 10, 2025

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Published on: April 19, 2024
Repeat pulmonary resection for lung malignancies does not affect the postoperative complications: a retrospective
Nozomu Motono1, Shun Iwai2, Yoshihito Iijima2
1Department of Thoracic Surgery, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa, 920-0293, Japan. motono@kanazawa-med.ac.jp.
Repeat pulmonary resection (RPR) for lung cancer is safe and feasible. This study found RPR is not associated with increased postoperative complications, even when performed on the same side of the chest.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Pulmonary Medicine
Background:
- Repeat pulmonary resection (RPR) is performed for multiple lung cancers, including non-small cell lung cancer and metastatic lung tumors.
- While prognostic benefits are reported, the risks associated with RPR require thorough analysis.
Purpose of the Study:
- To analyze the risks and postoperative complications associated with repeat pulmonary resection (RPR).
- To identify factors influencing postoperative complications in patients undergoing RPR.
Main Methods:
- Analysis of 41 patients who underwent complete resection for lung malignancies between 2010 and 2019.
- Evaluation of the relationship between postoperative complications (Clavien-Dindo classification) and preoperative/perioperative factors.
- Comparison of complication rates between ipsilateral and contralateral RPR.
Main Results:
- The overall postoperative complication rate was 29% for both the first and second operations.
- No significant factors for increased complications were found in multivariate analysis, though longer operation times (>2 hours) at the second operation showed a trend towards increased complications.
- Operation time was significantly longer in the ipsilateral group compared to the contralateral group, with a trend towards longer wound length.
Conclusions:
- Repeat pulmonary resection (RPR) is a safe and feasible procedure.
- RPR is not associated with an increased rate of postoperative complications, even when performed on the ipsilateral side.
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