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Updated: Sep 9, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
Moving beyond treatment: pulmonary function, autonomous motivation, and physical activity enjoyment in adults with
Wolfgang Gruber1,2, Matthias Welsner3, Florian Stehling4
1Paediatric Pulmonology and Sleep Medicine, Cystic Fibrosis Centre, Children´S Hospital, University of Duisburg-Essen, 45147, Essen, Germany. wolfgang.gruber@uk-essen.de.
Background:
Physical activity (PA) and structured exercise are established cornerstones of cystic fibrosis (CF) management. While CFTR modulators have transformed treatment, the psychological factors affecting sustained PA adherence, particularly motivational regulation and PA enjoyment, require further investigation. This study aimed to determine whether percent predicted forced expiratory volume in one second (ppFEV₁) is independently associated with autonomous motivation and PA enjoyment in adults with CF, after adjusting for CFTR modulator therapy status and sex.
Methods:
A cross-sectional study was conducted at a specialised CF centre (N = 200). Participants completed validated questionnaires assessing motivational regulation (Behavioural Regulation Questionnaire-2, BREQ-2) and PA enjoyment (Physical Activity Enjoyment Scale, PACES). Clinical data, including the ppFEV₁, were obtained from medical records. Multivariate general linear models (GLM), partial correlations, and hierarchical regression analyses were utilised.
Results:
Cross-sectional analyses showed that ppFEV₁ was independently associated with intrinsic motivation (β = .233, p < .001), the relative autonomy index (RAI) (β = .203, p = .004) and the PACES total score (β = .201, p = .004). After CFTR modulator therapy status and sex were accounted for, the additional variance explained by the ppFEV₁ was statistically significant but modest (ΔR2 = .054, .041, and .040, respectively). Neither the CFTR modulator therapy status nor sex was significantly associated with the assessed motivational or enjoyment outcomes.
Conclusions:
Although ppFEV₁ showed small, independent associations with autonomous motivational regulation and PA enjoyment in adults with CF, lung function should not be used as a proxy for motivational support needs. To provide person-centred, SDT-informed support that encourages sustained participation in PA, the motivational regulation and enjoyment of PA should be assessed directly in adults with CF.
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