Related Experiment Video

Updated: Nov 10, 2025

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

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Maternal asthma during pregnancy and risks of allergy and asthma in progeny: a systematic review protocol

Andrea J Roff1,2, Janna L Morrison3, Andrew Tai1,2,4

  • 1Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia.

JBI Evidence Synthesis
|April 2, 2021
PubMed

Insights

Maternal asthma during pregnancy increases offspring allergy risk. This review synthesizes evidence on prenatal asthma exposure and postnatal allergies in children, examining asthma severity impacts.

Area of Science:

  • Reproductive immunology
  • Pediatric allergy
  • Epidemiology

Background:

  • Maternal asthma is a known risk factor for childhood asthma.
  • Emerging evidence links maternal asthma to increased allergy risk in offspring, suggesting non-genetic factors.
  • The precise relationship between maternal asthma severity during pregnancy and offspring allergy is not fully understood.

Purpose of the Study:

  • To systematically review and synthesize evidence on the association between in utero exposure to maternal asthma and postnatal allergy in children.
  • To investigate how maternal asthma control, exacerbations, and severity during pregnancy influence the risk of allergy and asthma in offspring.

Main Methods:

  • Systematic review of primary studies.
  • Inclusion of studies reporting physician-diagnosed asthma or allergic disease in children exposed to maternal asthma in utero versus unexposed controls.
  • Comprehensive database searches (PubMed, Embase, etc.) with no date restrictions, English full-text only.

Main Results:

  • This section is to be populated upon completion of the review.

Conclusions:

  • This section is to be populated upon completion of the review.
Abstract

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