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Updated: Nov 10, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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COR758, a negative allosteric modulator of GABAB receptors

Alessandra Porcu1, Rafaela Mostallino2, Valeria Serra2

  • 1Department of Biomedical Sciences, University of Cagliari, 09042, Monserrato, Italy; Department of Biomedicine, University of Basel, Klingelbergstrasse 50-70, CH-4056, Basel, Switzerland.

Neuropharmacology
|April 2, 2021
PubMed

Keywords:
Allosteric modulatorsBioluminescence resonance energy transfer (BRET)GABA(B) receptorsGTPγS bindingNegative allosteric modulator (NAM)

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