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Related Experiment Video

Updated: Nov 10, 2025

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Clear Aligners: Between Evolution and Efficiency-A Scoping Review.

Alessandra Putrino1, Ersilia Barbato1, Gabriella Galluccio1

  • 1Department of Oral and Maxillofacial Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.

International Journal of Environmental Research and Public Health
|April 3, 2021
PubMed
Summary
This summary is machine-generated.

Clear aligner technology has advanced significantly in materials and design, expanding treatment options. Further research is needed on diverse aligner systems beyond Invisalign to support their widespread market use.

Keywords:
attachmentsauxiliariesbiomechanicsclear alignersdivotsefficacyefficiencyelasticsmini-screwsorthodontics

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Area of Science:

  • Orthodontics
  • Biomaterials Engineering

Background:

  • Clear aligners have evolved with diverse characteristics like material, gingival margin design, attachments, and auxiliaries.
  • This evolution has broadened their clinical indications and treatment efficiency.

Purpose of the Study:

  • To review the evolution of clear aligner systems available in Italy.
  • To analyze aligner characteristics based on current scientific literature.

Main Methods:

  • A literature review was conducted using major scientific databases (PubMed, Scopus, Lilacs, Google Scholar, Cochrane Library).
  • Inclusion and exclusion criteria were applied, and data were collected and descriptively analyzed.
  • 31 studies were included after screening 580 initial records.

Main Results:

  • The review identified advancements in clear aligner materials and designs, enhancing their efficacy.
  • Gingival margin design and auxiliary features are underrepresented in recent literature.
  • Knowledge of basic aligner system characteristics is clearer, but research on non-Invisalign systems is limited.

Conclusions:

  • Current clear aligner knowledge is substantial, but requires expansion beyond dominant systems.
  • Further investigation into diverse aligner systems is necessary to support their clinical application and market presence.