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Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

637
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
637
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

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The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
902

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Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications
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Hydrogel-Core Microstructured Polymer Optical Fibers for Selective Fiber Enhanced Raman Spectroscopy.

Mikel Azkune1, Igor Ayesta2, Leire Ruiz-Rubio3,4

  • 1Department of Electronic Technology, Engineering School of Bilbao, University of the Basque Country (UPV/EHU), Torres Quevedo 1, 48013 Bilbao, Spain.

Sensors (Basel, Switzerland)
|April 3, 2021
PubMed
Summary
This summary is machine-generated.

This study introduces a novel Fiber Enhanced Raman Spectroscopy (FERS) method using Hydrogel-Core microstructured Polymer Optical Fibers (HyC-mPOF) for highly selective measurements in functionalized matrices.

Keywords:
Fiber Enhanced Raman Spectroscopyhydrogel-core mPOFliquid-core mPOFmicrostructured Polymer Optical Fibers

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Area of Science:

  • Optics and Photonics
  • Materials Science
  • Spectroscopy

Background:

  • Fiber Enhanced Raman Spectroscopy (FERS) offers high sensitivity for molecular detection.
  • Microstructured Polymer Optical Fibers (mPOFs) provide a versatile platform for optical sensing.
  • Functionalized sensing matrices are crucial for selective analyte detection.

Purpose of the Study:

  • To develop and demonstrate a novel FERS platform using Hydrogel-Core mPOFs (HyC-mPOF).
  • To enable highly selective Raman measurements within a functionalized matrix.
  • To validate the performance of the HyC-mPOF platform for detecting target molecules.

Main Methods:

  • Fabrication of Hollow-Core mPOFs with hydrogel incorporation in the core (HyC-mPOF).
  • Continuous monitoring and quantification of hydrogel formation using Principal Component Analysis (PCA).
  • Performing FERS measurements with high and low affinity target molecules.

Main Results:

  • Successful integration of hydrogel within the HC-mPOF core.
  • PCA effectively verified hydrogel component coherence with Raman spectra.
  • Demonstrated feasibility of HyC-mPOF for selective FERS detection of target molecules.

Conclusions:

  • The HyC-mPOF platform enables selective FERS measurements in a functionalized matrix.
  • This approach enhances selectivity in Raman spectroscopy applications.
  • The developed platform shows promise for sensitive and specific molecular detection.