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Updated: Nov 10, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Novel Strategies for Treating Castration-Resistant Prostate Cancer
David Ka-Wai Leung1, Peter Ka-Fung Chiu1, Chi-Fai Ng1
1S. H. Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Abstract:
The development of castration resistance is an inevitable pathway for the vast majority of patients with advanced prostate cancer. Recently, there have been significant breakthroughs in the understanding and management options of castration-resistant prostate cancer. Three novel hormonal agents showed survival benefits in non-metastatic patients. As for metastatic disease, there was an even wider range of management options being investigated. This review summarized advances in the management of castration-resistant prostate cancer (CRPC) including emerging data on novel imaging techniques and treatment strategies.
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