Influence of sodium balance on uremic red blood cell ion transport

¹Department of Internal Medicine, University of Liège, CHU Sart Tilman, Belgium.

|January 1, 1988

Abstract:

This study was performed to test the effect of dialysis-induced acute modifications of plasma volume and sodium pool on red blood cell (RBC) ion transport in patients with end-stage renal disease. This approach confirmed the presence of an Na-K pump inhibitor in the plasma of uremic patients with extracellular fluid volume expansion. This factor cross-reacts with digoxin antibodies, and its concentration decreases during dialysis; this explains the increased activity of the RBC Na-K pump that is consistently observed during dialysis.

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Abstract:

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