Related Experiment Video
Updated: Nov 10, 2025

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
Published on: May 27, 2021
Current Knowledge about Providing Drug-Drug Interaction Services for Patients-A Scoping Review
Tora Hammar1, Sara Hamqvist2, My Zetterholm1,3
1Department of Medicine and Optometry, The eHealth Institute, Linnaeus University, 391 82 Kalmar, Sweden.
Digital drug-drug interaction (DDI) services can aid patients, but quality varies significantly. Further research is needed to ensure safe and effective patient-facing DDI tools.
Area of Science:
- Health Informatics
- Patient Safety
- Digital Health
Background:
- Drug-drug interactions (DDIs) are a significant patient safety concern.
- eHealth solutions offer potential to improve medication management for professionals and patients.
- While clinical decision support systems (CDSS) for professionals are well-researched, patient-focused DDI support is less understood.
Purpose of the Study:
- To explore and describe the current knowledge on digital drug-drug interaction (DDI) services for patients.
- To identify existing DDI support services and understand patient demands and capabilities.
Main Methods:
- A scoping review was conducted using a broad search strategy.
- An established framework for scoping reviews was applied.
- Nineteen relevant papers were included in the analysis.
Main Results:
- Some patients desire to self-check for DDIs, with varying demands and abilities.
- Numerous digital DDI services exist, but quality variations pose potential safety risks.
- Suggestions for design features were identified, alongside a significant knowledge gap.
Conclusions:
- Patient-centered digital DDI services require careful design to ensure safety and avoid unintended consequences.
- Further research is essential to determine optimal methods for providing digital DDI support to patients.
- Addressing the variations in service quality is crucial for enhancing patient safety in digital health interventions.
Related Concept Videos
Pharmacokinetics: Drug–Drug Interactions
Pharmacokinetics: Drug–Food and Drug–Viral Interactions
Drug Dosing: Geriatric Patients
Agonism and Antagonism: Quantification
To quantify these effects, researchers use a dose-response curve, which provides valuable information about the potency and efficacy of a drug. Potency refers to...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Drug Administration and Therapy Phases: Overview
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...

