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Synthesis of hexanucleotide analogues containing diisopropylsilyl internucleotide linkages
1Department of Chemistry, McGill University, Montreal, Quebec, Canada.
Nucleic Acids Research
|May 25, 1988
Abstract:
The synthesis of two silyl-linked hexanucleotide analogues is described. Hypochromicity and CD measurements indicate that the thymidine hexanucleotide analogue bears a strong resemblance to its phosphodiester-linked counterpart.