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Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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Spt4 Promotes Pol I Processivity and Transcription Elongation

Abigail K Huffines1, Yvonne J K Edwards1, David A Schneider1

  • 1Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham 720 20th Street South, Birmingham, AL 35294, USA.

Genes
|April 3, 2021
PubMed
Summary

The Spt4 protein is crucial for RNA Polymerase I (Pol I) transcription elongation in yeast. Deleting SPT4 impairs Pol I processivity, especially in G-rich ribosomal DNA regions.

Keywords:
RNA polymerase ISpt4rRNAribosometranscription

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