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Updated: Nov 10, 2025

µTongue: A Microfluidics-Based Functional Imaging Platform for the Tongue In Vivo
Published on: April 22, 2021
Geographic tongue as a reaction-diffusion system
Margaret K McGuire1, Chase A Fuller1, John F Lindner1
1Department of Physics, The College of Wooster, Wooster, Ohio 44691, USA.
Abstract:
Geographic tongue or benign migratory glossitis is a condition of an unknown cause characterized by chronic lesions that slowly migrate across the surface of the tongue. The condition's characteristic wavefronts suggest that it can be modeled as a reaction-diffusion system. Here, we present a model for geographic tongue pattern evolution using reaction-diffusion equations applied to portions of spheroids and paraboloids that approximate a tongue shape. We demonstrate that the observed patterns of geographic tongue lesions can be explained by propagating reaction-diffusion waves on these variably curved surfaces.
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