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Mannosidosis in a litter of Persian cats
T Maenhout1, J A Kint, G Dacremont
1Department of Veterinary Pathology, Faculty of Veterinary Medicine, State University of Ghent, Belgium.
The Veterinary Record
|April 9, 1988
Abstract:
Three kittens in a litter of Persian cats showed, from the age of eight weeks, tremor, ataxia, dysmetria, progressive weakness and emaciation. Cytoplasmic vacuolation was observed in neurons, mesenchymal and epithelial cells of tissues taken post mortem. The alpha-mannosidase activity of brain tissue of one cat tested was 4.8 per cent of control values and the urine of two cats contained large amounts of mannose-rich oligosaccharides.