Related Experiment Video
Updated: Nov 10, 2025
05:53
Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
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Frailty and HIV: Moving from Characterization to Intervention
Kristine M Erlandson1,2, Damani A Piggott3,4
1Department of Medicine, Division of Infectious Diseases, University of Colorado-Anschutz Medical Campus, 12700 E. 19th Avenue, Mail Stop B168, Aurora, CO, 80045, USA. Kristine.erlandson@cuanschutz.edu.
Current HIV/AIDS Reports
|April 5, 2021
Summary
Interventions for frailty in people with HIV (PWH) are emerging. Nonpharmacologic approaches like exercise and nutrition show promise for improving frailty components in PWH.
Area of Science:
- Gerontology
- Infectious Diseases
- Public Health
Background:
- Frailty is increasingly recognized in people with HIV (PWH).
- Understanding interventions to manage frailty in PWH is crucial.
Purpose of the Study:
- To review interventions for preventing or treating frailty.
- To examine interventions in the general population and in PWH.
Main Methods:
- Literature review of frailty interventions.
- Focus on nonpharmacologic and pharmacologic approaches.
Main Results:
- Nonpharmacologic interventions (exercise, nutrition) benefit frailty components in PWH.
- Pharmacologic interventions show limited clinical data in older adults with or without HIV.
Conclusions:
- Nonpharmacologic interventions are primary for PWH frailty.
- Pharmacologic interventions require more clinical investigation for PWH.
- Interventions hold potential to mitigate frailty vulnerability in PWH, but data is sparse.
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