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Myoclonus-Ataxia Syndrome Associated with COVID-19
Kuldeep Shetty1, Atul Manchakrao Jadhav1, Ranjith Jayanthakumar2
1Department of Neurology, Mazumdar Shaw Medical Center, Narayana Hrudayalaya Hospital, Bangalore, India.
A rare neurological condition, myoclonus-ataxia syndrome, can occur after COVID-19 infection. Steroid treatment fully resolved symptoms, suggesting an immune-mediated cause.
Area of Science:
- Neurology
- Infectious Diseases
- Immunology
Background:
- Neurological complications of COVID-19 are increasingly recognized.
- The pandemic has highlighted novel post-infectious syndromes.
Observation:
- A patient developed disabling myoclonus and truncal cerebellar ataxia during convalescence from COVID-19.
- Initial neurological workups and infection tests were negative, but COVID-19 titers were high.
Findings:
- The patient's symptoms responded partially to antimyoclonic drugs.
- Complete symptom resolution occurred after a course of steroids, indicating immune-mediated pathophysiology.
Implications:
- Myoclonus-ataxia syndrome is a potential neurological sequela of COVID-19.
- Increased clinician awareness is crucial for managing this post-infectious immune-mediated condition.
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