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Related Experiment Videos

[Extracorporeal lithotripsy and prophylactic antibiotic therapy].

B Gattegno1, F Sicard, D Alcaidinho

  • 1Clinique Urologique, Hôpital Tenon, Paris.

Annales D'Urologie
|January 1, 1988
PubMed
Summary

Prophylactic antibiotics are not necessary for patients undergoing extracorporeal shock wave lithotripsy (ESWL) when pre-procedure urine cultures are negative. This study found minimal infection risk, suggesting routine antibiotic use is not required for sterile urine cases.

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Area of Science:

  • Urology
  • Infectious Diseases
  • Nephrology

Background:

  • Extracorporeal shock wave lithotripsy (ESWL) can disintegrate stones, potentially releasing bacteria.
  • The risk of infectious complications following ESWL, particularly when urine is sterile, requires evaluation.
  • Prophylactic antibiotic use is a common consideration to mitigate infection risk.

Purpose of the Study:

  • To assess the efficacy of prophylactic antibiotic therapy in preventing infectious complications after ESWL.
  • To determine if routine antibiotic administration is necessary for patients with sterile urine undergoing ESWL.

Main Methods:

  • A randomized controlled trial involving 50 patients with negative pre-ESWL urine cultures.
  • Patients were divided into two groups: one received a placebo, and the other received a single intravenous dose of Ceftriaxone 1g one hour prior to ESWL.

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  • Urine and blood cultures were monitored post-procedure.
  • Main Results:

    • No positive blood cultures were observed in either the placebo or the antibiotic group.
    • No positive urine cultures were detected in either treatment arm.
    • The incidence of infectious complications was minimal in both groups.

    Conclusions:

    • Prophylactic antibiotic therapy does not appear to be necessary for patients undergoing ESWL when their pre-procedure urine culture is sterile.
    • The risk of infection induced by ESWL in patients with sterile urine is minimal.
    • Current findings suggest a conservative approach to antibiotic use in this specific patient population.