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Optic Neuritis After a Snakebite: A Diagnostic Dilemma.

Jeyhan Dhabhar1, Varshil Mehta2, Nimit Desai3

  • 1Department of Internal Medicine, MGM Medical College, Navi Mumbai, India.

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|April 8, 2021
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Summary

Snakebite envenoming in India can cause severe neurotoxicity. This case highlights optic neuropathy as a rare complication, emphasizing prompt diagnosis and treatment with antivenom and steroids for a good prognosis.

Keywords:
Delayed diagnosiselapidaeneurotoxicity syndromessnake bites

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Area of Science:

  • Neurology
  • Toxicology
  • Ophthalmology

Background:

  • Snakebite envenoming is a significant public health issue in India, leading to considerable morbidity and mortality, especially in rural areas.
  • Elapidae snakes, including the cobra and common krait, are primarily responsible for neurotoxic effects, often resulting in acute neuromuscular weakness and respiratory compromise.

Observation:

  • A 24-year-old female presented with unresponsiveness after a snakebite, requiring intubation and mechanical ventilation.
  • Following initial improvement with antivenom and anticholinesterase agents, the patient developed blurred vision and slurred speech on day 6, indicative of bilateral optic neuropathy.

Findings:

  • The patient was treated with repeat snake antivenom and steroids for optic neuritis, leading to significant clinical improvement.
  • Discharge occurred on day 14, demonstrating the efficacy of timely and comprehensive management for this rare snakebite complication.

Implications:

  • While antivenom is crucial for snakebite management, clinicians must remain vigilant for potential neurological and ophthalmological complications.
  • Optic neuritis following snakebite, though uncommon, necessitates early recognition and aggressive treatment with steroids and antivenom for favorable outcomes.
  • This case underscores the importance of identifying the snake species and considering rare adverse events in the clinical suspicion and management of snakebite victims.