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Updated: Jul 26, 2026

Preparation of Aplysia Sensory-motor Neuronal Cell Cultures
Published on: June 8, 2009
A calcium-activated, nonselective cationic conductance in Aplysia silent neurons
1Department of Pediatrics (Neurology), Duke University Medical Center, Durham, NC 27710.
Abstract:
We have previously reported the activation of a triphasic current response by calcium injection in voltage-clamped, nonbursting neurons of Aplysia californica. Present evidence indicates that the second phase, a delayed inward current that peaks 10-20 seconds after the end of the injection, is a calcium-activated, nonselective cationic conductance. It can be carried by both sodium and calcium, is not sensitive to chloride concentration changes, but is voltage sensitive, decreasing in amplitude with hyperpolarization.
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