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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Relation between Serum Magnesium Level and Migraine.

M R Karim1, M Bhattacharjee, M S Islam

  • 1Dr Md Rezaul Karim, Registrar (Neurology), Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh;

Mymensingh Medical Journal : MMJ
|April 8, 2021
PubMed
Summary
This summary is machine-generated.

Migraine patients in Bangladesh showed significantly lower serum magnesium levels compared to those without migraines. Lower magnesium was also observed in individuals experiencing severe migraine headaches.

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Area of Science:

  • Neurology
  • Biochemistry

Background:

  • Migraine is a highly disabling headache disorder affecting a significant portion of the population, particularly women.
  • The exact mechanisms of migraine are not fully understood, but serum magnesium levels are being investigated as a potential factor.

Purpose of the Study:

  • To investigate serum magnesium levels in migraine patients within Bangladesh.
  • To determine any correlation between serum magnesium levels and migraine severity.

Main Methods:

  • A cross-sectional analytical study was conducted with 70 migraine patients and a control group.
  • Serum magnesium levels were measured and compared between groups, excluding specific confounding factors.
  • Demographic and clinical data, including headache severity and family history, were collected.

Main Results:

  • Migraine patients exhibited significantly lower mean serum magnesium levels (1.70 mg/dl) compared to the non-migraine group (1.85 mg/dl).
  • Serum magnesium levels were also lower in migraine patients experiencing severe headaches versus mild to moderate headaches.
  • No significant differences in serum magnesium were found based on age, sex, attack frequency, or aura presence.

Conclusions:

  • Serum magnesium levels are significantly lower in migraine patients compared to non-migraine individuals.
  • Lower serum magnesium is associated with increased migraine headache severity.
  • These findings suggest a potential role for magnesium in migraine pathophysiology.