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Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Published on: July 10, 2012

Urgent lung transplantation for thymic neoplasm-associated severe constrictive bronchiolitis with bronchiectasis and

Tomaž Štupnik^1,2, Marija Iča Dolenšek³, Jernej Mlakar⁴

¹Department of Thoracic Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Thoracic Cancer

|April 8, 2021

Abstract:

Here, we present the case of a 28-year-old woman who developed severe and progressive thymoma-associated constrictive bronchiolitis with bronchiectasis, despite undergoing thymectomy. The disease was further complicated by radiation-induced organizing pneumonia (RIOP), which developed after adjuvant radiotherapy (RT) for Masaoka stage II thymoma. The patient was successfully treated with an urgent lung transplantation (LTx) for irreversible respiratory failure.

Keywords:

end-stage lung disease lung transplantation radiation induced organizing pneumonia thymic neoplasm-associated bronchiolitis

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Clinical Manifestations:

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