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Updated: Nov 9, 2025

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
[Egg allergy in children and adults]
Haïg Nigolian1, Jean-Christoph Caubet2, Yann Coattrenec1
1Service d'immunologie et d'allergologie, Département de médecine, HUG, 1211 Genève 14.
Hen's egg allergy is a common childhood food allergy. Diagnosis involves history and tests, with management including emergency kits and oral tolerance induction for select patients.
Area of Science:
- Immunology
- Pediatrics
- Allergology
Background:
- Hen's egg allergy is the second most frequent food allergy in children, rarely occurring in adults.
- Symptoms can be varied and severe, posing challenges for both patients and healthcare providers.
- Accurate diagnosis and effective management are crucial for improving patient outcomes.
Purpose of the Study:
- To provide a comprehensive overview of hen's egg allergy in children.
- To outline diagnostic approaches and management strategies.
- To highlight the importance of specialized care and emerging treatments.
Main Methods:
- Review of current literature and clinical guidelines on hen's egg allergy.
- Analysis of diagnostic tools including allergy history, skin prick tests, and specific IgE testing.
- Evaluation of management strategies such as allergen avoidance, emergency preparedness, and oral tolerance induction.
Main Results:
- Allergy history is the primary diagnostic method, often supplemented by skin tests and specific IgE.
- Patients with egg anaphylaxis require emergency kits and specialized allergologic assessment.
- Strict egg avoidance is challenging due to hidden allergens; oral tolerance induction is beneficial for selected individuals.
- Pre-vaccination assessment is necessary in rare cases.
Conclusions:
- Hen's egg allergy requires a multi-faceted approach involving accurate diagnosis, vigilant management, and patient education.
- Specialized allergologic evaluation and tailored treatment plans, including oral tolerance induction, are key to managing this condition.
- Ongoing research is vital for developing safer and more effective strategies for children with egg allergy.
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