Related Experiment Video
Updated: Nov 9, 2025
11:54
Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry
Published on: July 13, 2019
9.1K
The Polyomavirus Episteme: A Database for Researchers
María José Andrade1, Gau Shoua Vue2, Michael J Imperiale3
1Swarthmore College, Swarthmore, Pennsylvania, USA.
Microbiology Resource Announcements
|April 9, 2021
Summary
Polyomaviruses are DNA viruses infecting diverse species. The Polyomavirus Episteme database consolidates taxonomic, genomic, and clinical data for these viruses, aiding research.
Area of Science:
- Virology
- Bioinformatics
- Genomics
Background:
- Polyomaviridae are DNA viruses with a broad host range.
- Numerous polyomaviruses have been identified since 1953 due to technological progress.
- Existing data on polyomaviruses is dispersed across various public resources.
Purpose of the Study:
- To create a centralized, curated database of polyomavirus information.
- To consolidate taxonomic, genomic, and clinical data for polyomaviruses.
- To facilitate research and understanding of the Polyomaviridae family.
Main Methods:
- Data mining from public biological databases.
- Information curation and organization.
- Development of the Polyomavirus Episteme database structure.
Main Results:
- A comprehensive repository of polyomavirus data has been established.
- Information on taxonomy, genomes, and clinical relevance is now accessible.
- The database provides a unified resource for researchers.
Conclusions:
- The Polyomavirus Episteme serves as a valuable resource for the scientific community.
- Centralized data enhances the study of polyomavirus diversity and impact.
- This curated database supports future research in virology and related fields.
More Related Videos
Related Concept Videos
01:29Viruses with RNA Genomes
333
RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
333
03:18Non-LTR Retrotransposons
12.5K
As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
12.5K