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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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[Pathogenetic and therapeutic aspects of cardioembolic stroke]

A V Romanenko1, E Yu Solovyeva1

  • 1Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|April 9, 2021
PubMed

Insights

Cardioembolic stroke (CS) is a severe ischemic stroke subtype needing monitoring. This review covers CS causes, thrombus formation, diagnosis, and anticoagulant therapy for prevention.

Area of Science:

  • Neurology
  • Cardiology
  • Vascular Medicine

Background:

  • Cardioembolic stroke (CS) is a severe subtype of ischemic stroke.
  • CS is associated with significant neurological deficits and high mortality.
  • Management requires collaboration between neurologists and cardiologists.

Purpose of the Study:

  • To review the causes and mechanisms of cardioembolic stroke.
  • To outline current diagnostic criteria and therapeutic strategies for CS.
  • To provide recommendations for anticoagulant therapy in CS prevention.

Main Methods:

  • Literature review of cardioembolic stroke.
  • Analysis of etiopathogenesis of cardiac thrombus formation.
  • Evaluation of current diagnostic and treatment guidelines.

Main Results:

  • CS presents with severe neurological deficits and increased risk of recurrence.
  • Thrombus formation in the heart is a key factor in CS.
  • Anticoagulant therapy is crucial for primary and secondary prevention.

Conclusions:

  • Effective management of CS necessitates understanding its cardiac origins.
  • Timely diagnosis and appropriate anticoagulant therapy improve patient outcomes.
  • Multidisciplinary care is essential for optimizing CS treatment and prevention.

Keywords:
anticoagulant therapycardioembolic strokediagnostic criteria

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