Related Experiment Videos
[Effect of the chemical structure of low molecular weight hapten carriers on immunoreactivity]
G Schwartze1, D Lübbe, K D Wozniak
1Klinik und Poliklinik für Hautkrankheiten, Bereiches Medizin der Martin-Luther-Universität Halle-Wittenberg.
Dermatosen in Beruf Und Umwelt. Occupation and Environment
|March 1, 1988
Abstract:
Patients with demonstrated contact dermatitis to DNCB (dinitrochlorobenzene) were patch-tested using various dinitrophenyl (DNP) derivatives. These investigations revealed the varying sensitivities to the structural isomers DNP-L-alpha-alanine (59% positive) and DNP-beta-alanine (4% positive). These results are discussed both in connection with various sensitivity rates to other DNP compounds and published findings from the literature concerning the influence of structural factors on immune reactivity.