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Updated: Nov 9, 2025

Dissection of Larval Zebrafish Gonadal Tissue
Published on: April 26, 2017
The Curious Case of Avian Sex Determination
Craig A Smith1, Andrew T Major1, Martin A Estermann1
1Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Abstract:
Ioannidis and colleagues show that the gene DMRT1 is the master regulator of testis development in the chicken. Yet, remarkably, when this gene is deleted in genetic males and gonads form ovaries, the body remains male. This debunks the notion that somatic sex is driven primarily by hormones in birds.
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