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Updated: Nov 9, 2025

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg
Published on: November 19, 2019
Endoscopic vein harvesting
Enoch Akowuah1, Daniel Burns2, Joseph Zacharias3
1Department of Cardiac Surgery, James Cook University Hospital, South Tees NHS, Foundation Trust, Middlesbrough, UK.
Insights
Endoscopic vein harvest (EVH) offers significant advantages over open vein harvest (OVH) for coronary artery bypass grafting, with no increased risk of adverse cardiac events. EVH is now recommended in major surgical guidelines.
Area of Science:
- Cardiovascular Surgery
- Minimally Invasive Procedures
- Vascular Grafting
Background:
- Coronary artery bypass grafting (CABG) frequently uses the long saphenous vein as a conduit.
- Open vein harvest (OVH) involves lengthy leg incisions (up to 85cm), leading to significant morbidity.
- Endoscopic vein harvest (EVH) emerged as a less invasive alternative, showing reduced wound complications and faster recovery.
Purpose of the Study:
- To evaluate the safety and efficacy of EVH compared to OVH in CABG procedures.
- To address concerns regarding the impact of EVH on vein graft patency and major adverse cardiac events (MACE).
Main Methods:
- Review of clinical trials and large observational studies comparing EVH and OVH.
- Analysis of data on leg wound complications, graft patency, and MACE.
- Consideration of current international surgical guidelines.
Main Results:
- EVH significantly reduces leg wound complications, including surgical site infections, compared to OVH.
- Initial concerns regarding increased mortality with EVH were debunked by large observational studies.
- A 2019 randomized controlled trial confirmed no increase in death, myocardial infarction, or repeat revascularization with EVH.
Conclusions:
- EVH is a safe and effective method for vein conduit harvesting in CABG.
- EVH offers advantages in terms of reduced patient morbidity and faster recovery.
- EVH is supported by strong clinical evidence and is recommended in major cardiothoracic surgery guidelines.
Abstract:
Coronary artery bypass grafting is the most common cardiac surgical procedure performed worldwide and the long saphenous vein the most common conduit for this. When performed as an open vein harvest (OVH), the incision on each leg can be up to 85cm long, making it the longest incision of any routine procedure. This confers a high degree of morbidity to the procedure. Endoscopic vein harvest (EVH) methods were popularised over two decades ago, demonstrating significant benefits over OVH in terms of leg wound complications including surgical site infections. They also appeared to hasten return to usual activities and wound healing and became popular particularly in North America. Subgroup analyses of two trials designed for other purposes created a period of uncertainty between 2009-2013 while the impact of endoscopic vein harvesting on vein graft patency and major adverse cardiac events was scrutinised. Large observational studies debunked the findings of increased mortality in the short-term, allowing practitioners and governing bodies to regain some confidence in the procedure. A well designed, adequately powered, randomised controlled trial published in 2019 also definitively demonstrated that there was no increase in death, myocardial infarction or repeat revascularisation with endoscopic vein harvest. Endoscopic vein harvest is a Class IIa indication in European Association of Cardio-Thoracic Surgery (EACTS) and a Class I indication in International Society of Minimally Invasive Cardiac Surgery (ISMICS) guidelines.
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