Radiographic case report of a heart transplanted patient suffering from COVID-19

Leona S Alizadeh1,2, Moritz H Albrecht1, Christian Booz1

  • 1Department of Diagnostic and Interventional Radiology, University Hospital, Frankfurt, Germany.

Heliyon
|April 12, 2021
PubMed

Insights

This case study highlights an atypical presentation of Coronavirus disease 2019 (COVID-19) in a heart transplant recipient. Despite multiple risk factors, the patient experienced mild symptoms and unusual CT scan results during hospitalization.

Area of Science:

  • Medical Science
  • Infectious Diseases
  • Cardiology

Background:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a significant risk to elderly patients with comorbidities and male individuals.
  • Typical computed tomography (CT) findings in Coronavirus disease 2019 (COVID-19) include bilateral ground glass opacities, septal thickening, and consolidation.

Observation:

  • A 77-year-old heart transplant recipient with pre-existing coronary heart disease and diabetes type II was diagnosed with COVID-19.
  • The patient presented with only mild clinical symptoms throughout the course of the disease.
  • Serial CT scans revealed an atypical progression of pulmonary findings during hospitalization.

Findings:

  • The patient's clinical presentation was incongruent with their significant risk factors for severe COVID-19.
  • Computed tomography (CT) imaging demonstrated an unusual pattern and evolution of lung abnormalities, deviating from typical COVID-19 presentations.
  • The combination of comorbidities and transplant status may influence the manifestation and imaging characteristics of SARS-CoV-2 infection.

Implications:

  • This case underscores the variability in COVID-19 presentation, even in high-risk populations.
  • Atypical CT findings in immunocompromised patients warrant careful clinical correlation.
  • Further research is needed to understand the impact of comorbidities and immunosuppression on COVID-19 disease course and imaging.