Related Experiment Video
Updated: Nov 9, 2025
Author Spotlight: Advancing Varicocele Treatment with Neuromuscular Electrical Stimulation
Published on: August 30, 2024
Treatment of Localized Vulvar Pain with Neural Therapy: A Case Series and Literature Review
Modesto Rey Novoa1,2, Montserrat Muñoz-Sellart2,3,4, Marta Catalán Soriano2,5
1Department of Obstetrics and Gynecology, Hospital Universitario de Burgos, Burgos, Spain.
Background:
Localized vulvar pain (LVP) is a common condition among fertile women, with physical and psychosexual implications. Treatment is complex with limited benefits. Neural therapy is a regulatory therapy that uses injections of local anesthetics in low concentrations in specific points to treat different conditions.
Case Presentation:
We present the cases of 5 women, ages 33-44 years, with LVP treated with procaine 0.5% injections in painful points. Complete relief from pain occurred in 2 patients, and significant improvement in 3. Only 1 or 2 sessions were required. Initial VAS score was ≥70 and decreased to ≤30 after the intervention. The improvement was maintained over time, with a minimum follow-up period of 6 months. None of the patients were able to have sex or use tampons due to pain, but they were able to resume after the intervention.
Conclusions:
In this case series, local injections of procaine showed a favorable outcome. Future randomized clinical trials could help elucidate the role of this intervention in LVP.
