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Published on: September 5, 2017
Quantified TB Exposure Can Predict Prevalent TB Disease in Child Contacts
Amyn A Malik1,2,3, Farhana Amanullah4, Sara Siddiqui2
1From the Yale Institute for Global Health, New Haven, Connecticut.
Abstract:
In a matched case-control study in Pakistan, we found that quantified tuberculosis (TB) exposure using a 10-point score is associated with prevalent TB disease in pediatric household contacts. A 1 unit increase in TB exposure score increased the odds of TB disease by 44% (conditional odds ratio: 1.44, 95% confidence interval: 1.33-1.56). Collecting well-documented exposure history can help TB diagnosis in resource-limited settings.
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