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Primitive neuroectodermal tumor of the penile urethra
Ashishkumar Narsinhbhai Asari1, Bijal Kulkarni2, T B Yuvaraja1
1Department Uro-Oncology and Robotic Surgery, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, Maharashtra, India.
Primitive neuroectodermal tumor (PNET), a rare penile urethral cancer, requires consideration in young males with urethral masses. Early diagnosis and treatment are crucial for this aggressive malignancy.
Area of Science:
- Oncology
- Urology
Background:
- Primitive neuroectodermal tumors (PNET) are aggressive, malignant neoplasms.
- PNETs typically affect soft tissue and bone, with genitourinary involvement being rare.
Observation:
- A rare case of PNET originating in the penile urethra is presented.
- The patient, a 27-year-old male, exhibited penile swelling and urinary difficulty.
Findings:
- Urethroscopic biopsy and subsequent total penectomy confirmed penile urethral PNET.
- The tumor demonstrated aggressive biological behavior, necessitating combination chemotherapy (IE + VAC regimens).
Implications:
- PNET should be included in the differential diagnosis for penile urethral masses in young patients.
- This case highlights the importance of considering rare malignancies in genitourinary presentations.
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