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Updated: Nov 9, 2025

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Breast uptake on a myocardial perfusion scan
Cristina Cuaresma Morales1, Angelin Fragante Apostol1,2
1Nuclear Medicine Division, Philippine Heart Center, Quezon City, Philippines.
Myocardial perfusion scans (MPS) can incidentally detect breast masses. Careful review of raw images and fused CT scans revealed abnormal tracer uptake in nodular breast tissue, highlighting a potential for concurrent pathology detection.
Area of Science:
- Nuclear medicine
- Medical imaging
- Cardiology
Background:
- Myocardial perfusion scans (MPS) are primarily used for diagnosing coronary artery disease.
- Standard MPS protocols are not optimized for detecting extrathoracic or breast pathologies.
- Incidental findings on medical imaging require careful evaluation.
Observation:
- A 42-year-old female patient presented for MPS to assess coronary artery disease.
- Initial review of raw and cine loop MPS images showed unexpected tracer accumulation in the chest.
- Short-axis slices and low-dose CT images (used for attenuation correction) were analyzed.
Findings:
- Fusion of MPS and CT images localized the focal tracer uptake to nodular breast masses.
- The observed uptake indicated concurrent breast pathology not initially sought by the scan.
- This highlights the potential for MPS to reveal unexpected findings.
Implications:
- MPS, while not designed for breast imaging, can identify concurrent breast pathologies.
- Thorough review of unprocessed MPS images and utilization of image fusion software are crucial.
- This approach enhances diagnostic yield and can lead to early detection of incidental breast findings.
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