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Updated: Aug 11, 2026

Isolation of Brain-infiltrating Leukocytes
Published on: June 13, 2011
A RARE BRAINSTEM INFLAMMATORY SYNDROME, CLIPPERS, MYTH OR FACT. CASE REPORT WITH CRITICAL REVIEW
Pavel A Dyachenko1, Raisa A Hramova2, Anatoly G Dyachenko2
1CЕNTЕR OF INFECTIOUS DISORDERS OF THE NERVOUS SYSTEM, SI "L.V. GROMASHEVSKY INSTITUTE OF EPIDEMIOLOGY AND INFECTION DISEASESOF NAMS OF UKRAINE", KYIV, UKRAINE.
Abstract:
A very rare inflammatory disease of CNS, CLIPPERS syndrome, was recently described and only a few sporadic cases are reported in the medical literature. Its etiology and pathogenesis are unknown, that together with the polymorphic and sometimes confounding neurological manifestations, and radiological findings represent a real diagnostic and therapeutic challenge for clinicians. Aim: To highlight the importance of clear and specific diagnostic assessment. Here we present the case of a 40-year-old male with a subacute lymphocytic midbrain inflammation accompanied by vasculitis. We discuss the symptoms, imaging and treatment of this lesion.
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