Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

35.9K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
35.9K
Epigenetic Regulation01:37

Epigenetic Regulation

3.3K
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
3.3K
Epigenetic Regulation01:46

Epigenetic Regulation

31.9K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
31.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A 6-Item Diagnostic Screener for Childbirth-Related PTSD.

medRxiv : the preprint server for health sciences·2026
Same author

A scalable, low-cost, sample hashing workflow for multiomic single-cell analysis using the Seq-Well S<sup>3</sup> platform.

Nature protocols·2026
Same author

Fetal sex-specific differences in the placental transcriptome of gestational diabetes.

Scientific reports·2026
Same author

Application of Chorionic Villus Sampling to Longitudinal Studies in Pregnant Non-Human Primate Models.

Animals : an open access journal from MDPI·2026
Same author

Protein networks are influenced by maternal BMI and differentiate preterm birth types.

Communications medicine·2026
Same author

Dopaminergic mechanisms supporting hippocampal postencoding dynamics in humans.

Proceedings of the National Academy of Sciences of the United States of America·2026

Related Experiment Video

Updated: Nov 9, 2025

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:13

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

442

Imaging Epigenetics of Prenatal THC.

Nicole R Zürcher1, Victoria H J Roberts2, Matthias C Schabel3

  • 1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, United States.

ACS Chemical Neuroscience
|April 14, 2021
PubMed
Summary

Maternal marijuana use during pregnancy may cause epigenetic changes in the placenta and fetal brain, impacting offspring health. Further research is crucial to understand these effects on development and long-term well-being.

Keywords:
EpigeneticsTHCdelta-9-tetrahydrocannabinolhistone deacetylasemarijuanapositron emission tomographypregnancy

More Related Videos

Administration of &#916;9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

471
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.9K

Related Experiment Videos

Last Updated: Nov 9, 2025

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:13

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

442
Administration of &#916;9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

471
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.9K

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Epigenetics

Background:

  • Prenatal marijuana exposure is a growing concern with potential health implications for offspring.
  • Epigenetic alterations are suspected mechanisms linking maternal use to developmental outcomes.

Purpose of the Study:

  • To highlight the need for research on the impact of prenatal marijuana exposure on offspring health.
  • To discuss the role of epigenetic modifications in mediating these effects.
  • To introduce novel research methodologies for studying this issue.

Main Methods:

  • Review of current understanding of prenatal marijuana exposure effects.
  • Discussion of the potential for Positron Emission Tomography (PET) imaging.
  • Emphasis on longitudinal in vivo non-human primate studies.

Main Results:

  • Prenatal marijuana exposure may induce epigenetic alterations in key developmental tissues.
  • These alterations can affect both short- and long-term health trajectories of the offspring.
  • The precise mechanisms and extent of these changes require further investigation.

Conclusions:

  • There is a critical need to investigate the consequences of in utero marijuana exposure.
  • Advanced imaging and longitudinal studies are essential to elucidate epigenetic changes.
  • Understanding these effects is vital for safeguarding child development and health.