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Intensive Cryotherapy in the Emergency Department (ICED): A Randomized Controlled Trial.
Eric J Leroux1, Elizabeth A Kaufman2, Christian N Kontaxis3
1Eisenhower Health, Department of Emergency Medicine, Rancho Mirage, California.
The Western Journal of Emergency Medicine
|April 15, 2021
Summary
Intensive targeted cryotherapy significantly reduced pain and opioid use in emergency department patients with acute musculoskeletal injuries compared to chemical cold packs. This method offers superior analgesia and may decrease reliance on opioids.
Area of Science:
- Emergency Medicine
- Orthopedics
- Pain Management
Background:
- Effective pain management is crucial for treating musculoskeletal injuries in the emergency department (ED).
- Cryotherapy is a common modality for pain relief in such cases.
- Evaluating different cryotherapy methods is essential for optimizing patient care.
Purpose of the Study:
- To compare the efficacy of intensive targeted cryotherapy versus chemical cold packs for analgesia in acute musculoskeletal injuries.
- To assess the impact of these cryotherapy methods on opioid utilization in the ED.
Main Methods:
- A prospective, randomized, single-blind controlled trial involving adult ED patients with acute musculoskeletal pain.
- Patients received either intensive targeted cryotherapy (crushed wetted ice) or a chemical cold pack for 20 minutes.
- Pain scores were measured at baseline, 20 minutes, and 60 minutes post-application.
Main Results:
- Intensive targeted cryotherapy demonstrated significantly greater pain relief at 20 and 60 minutes compared to chemical cold packs (P < 0.05).
- Opioid administration in the ED was significantly lower in the intensive targeted cryotherapy group (6% vs 33%, P < 0.05).
- Patients receiving discharge opioid prescriptions had higher 60-minute pain scores.
Conclusions:
- Intensive targeted cryotherapy is more effective for analgesia in acute musculoskeletal injuries within the ED setting.
- This cryotherapy method shows potential for reducing opioid usage in emergency medicine.
- Targeted cryotherapy offers a promising alternative for pain management of acute injuries.

