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Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome
Magdalena Szydłowicz1, Barbara Królak-Olejnik2, Sergio L Vargas3
1Department of Biology and Medical Parasitology, Wroclaw Medical University, Wroclaw, Poland.
Abstract:
We describe the prevalence of Pneumocystis jirovecii in mother-infant pairs of very low birth weight newborns <32 weeks gestation. Molecular and microscopic methods were used for detection of P. jirovecii in patients' specimens. Pneumocystis DNA was detected in 8 nasopharyngeal aspirates (14%) of 56 newborns and in 7 oral washes (21%) of 34 mothers. Pneumocystis detection immediately after birth suggests the possibility of its transplacental transmission. Compared to noncolonized infants, more frequent occurrence of bronchopulmonary dysplasia was seen in colonized infants (P = .02), suggesting a potential clinical importance of this pathogen in abnormal lung development.
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