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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
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Related Experiment Video

Updated: Nov 9, 2025

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
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Electrodiagnostic Testing for Disorders of Peripheral Nerves.

Joseph M Choi1, Gianluca Di Maria2

  • 1Georgetown University, Washington, DC, USA; Department of Neurology, MedStar Washington Hospital Center, MedStar Georgetown University Hospital, 3800 Reservoir Road, PHC 7th Floor, Washington, DC 20007, USA.

Clinics in Geriatric Medicine
|April 16, 2021
PubMed
Summary

Nerve conduction studies and electromyography are essential diagnostic tools for peripheral nerve and muscle diseases. Understanding electrophysiology basics is crucial for accurate interpretation in clinical practice.

Keywords:
CTSElectromyographyNerve conduction studiesPolyneuropathyRadiculopathyUlnar neuropathy

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Area of Science:

  • Neurology
  • Clinical Electrophysiology

Background:

  • Neuromuscular diseases are prevalent, particularly in the elderly.
  • Aging populations are expected to increase the incidence of these conditions.
  • Accurate diagnosis relies on integrating electrophysiological findings with clinical context.

Purpose of the Study:

  • To highlight the fundamental principles of electrophysiology.
  • To serve as a reference for healthcare providers ordering electrodiagnostic studies.
  • To emphasize the role of nerve conduction studies and electromyography in diagnosing neuromuscular disorders.

Main Methods:

  • Nerve conduction studies (NCS).
  • Electromyography (EMG).
  • Interpretation within the clinical context of patient history and examination.

Main Results:

  • NCS and EMG are valuable extensions of the clinical neurological assessment.
  • These electrophysiological tests aid in diagnosing peripheral nerve, neuromuscular junction, and muscle diseases.
  • Results must be correlated with clinical findings for accurate diagnosis.

Conclusions:

  • Electrophysiology, including NCS and EMG, is indispensable for diagnosing a range of neuromuscular conditions.
  • A solid understanding of electrodiagnostic principles is vital for effective patient management.
  • These studies are crucial for neurologists managing patients with suspected or confirmed neuromuscular disorders.