Complete Genome Sequences of Three Invasive Strains of Streptococcus pyogenes Subtype emm5.23 Isolated in Scotland
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Published on: December 23, 2022
Davide Pagnossin1,2, Andrew Smith3,4, William Weir2
1Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, United Kingdom d.pagnossin.1@research.gla.ac.uk.
Abstract:
Streptococcus pyogenes emm5.23 is uncommon; however, it has recently been involved in a relatively high proportion of cases of invasive disease in Scotland. Here, we report the complete genome sequences of three emm5.23 isolates, which may be used as a reference for investigating the virulence and epidemiology of this strain.
Insights
The uncommon Streptococcus pyogenes emm5.23 strain is increasingly linked to invasive infections in Scotland. Researchers have sequenced three emm5.23 isolates to aid future virulence and epidemiology studies.
Area of Science:
- Microbiology
- Genomics
- Epidemiology
Background:
- Streptococcus pyogenes is a significant human pathogen.
- The emm5.23 strain is infrequently identified but has recently emerged in invasive disease cases in Scotland.
Purpose of the Study:
- To report the complete genome sequences of three Streptococcus pyogenes emm5.23 isolates.
- To provide genomic resources for studying the virulence and epidemiology of this strain.
Main Methods:
- Whole-genome sequencing of three Streptococcus pyogenes emm5.23 isolates.
- Bioinformatic analysis of the obtained genome sequences.
Main Results:
- Complete genome sequences for three emm5.23 isolates were generated.
- These sequences provide a reference for further investigation.
Conclusions:
- The availability of these genome sequences is crucial for understanding the recent rise in invasive emm5.23 infections.
- Further research can utilize these data to explore the strain's virulence factors and epidemiological spread.
