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Erosive Lichen Sclerosus-A Clinicopathologic Subtype.

Tania Day, Geoffrey Otton1, Graeme Dennerstein2

  • 1Maternity and Gynaecology, John Hunter Hospital, Newcastle, New South Wales, Australia.

Journal of Lower Genital Tract Disease
|April 16, 2021
PubMed
Summary
This summary is machine-generated.

Erosive lichen sclerosus (LS) is a distinct subtype presenting as red patches on hairless skin. Ulcerated LS, conversely, often results from trauma in uncontrolled dermatosis.

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Area of Science:

  • Dermatopathology
  • Dermatology

Background:

  • Lichen sclerosus (LS) is a chronic inflammatory dermatosis.
  • Clinicopathologic subtypes of LS require further definition.

Purpose of the Study:

  • To determine if erosive lichen sclerosus (LS) represents a distinct clinicopathologic subtype.
  • To differentiate erosive LS from ulcerated LS.

Main Methods:

  • Histopathologic review of 25 LS cases with erosion or ulceration.
  • Analysis of clinical data including demographics, comorbidities, and treatment response.

Main Results:

  • Erosive LS (10 cases) presented as red patches on hairless skin with gently sloping erosions.
  • Ulcerated LS (15 cases) was associated with diabetes and often presented as lichenified lesions with epidermal breaches.
  • Both subtypes showed response to treatment, with 50% complete resolution.

Conclusions:

  • Erosive LS is a unique subtype characterized by specific microscopic and clinical features.
  • Ulcerated LS is typically a secondary complication of untreated or poorly controlled LS.